Comparative Toxicogenomics, Volume 2

Comparative Toxicogenomics, Volume 2

* Publisher: Elsevier Science
* Number Of Pages: 352
* Publication Date: 2008-08-12
* ISBN-10 / ASIN: 0444532749
* ISBN-13 / EAN: 9780444532749
* Binding: Hardcover

Product Description:
Toxicogenomics analyses the activity of a particular toxin or chemical substance on living tissue based upon a profiling of its known effects on genetic material. Toxicogenomics is important because it may enhance understanding of mechanisms of toxicity, cellular defence systems, and drug action. If this technique is proven to work, it could be used in a similar way for toxicology and toxin-determination to DNA-testing in the forensic identification of individuals.

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Integrated Basic Sciences: PreTest Self-Assessment and Review

Product Details
»Book Publisher: McGraw-Hill/Appleton & Lange (01 November, 1998)
»ISBN: 007052551X
»Book author: Earl J. Brown
»Amazon Rating: 4.0

Book Description:
This new Pre-test title offers yet another tool for USMLE prep. This time, the basic science questions are integrated just as they are on the USMLE Step 1 exam. 151 clinical vignettes are also included and reinforced what’s tested on the exam. All answers are referenced to the current literature for those wanting to expand their study.

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Hole’s Human Anatomy & Physiology

Product Details
»Book Publisher: McGraw-Hill Science/Engineering/Math (06 July, 2002)
»ISBN: 0070272468
»Book author: David N. Shier, Jackie L. Butler, Ricki Lewis
»Amazon Rating: 5.0

Book Description:
Hole’s Human Anatomy and Physiology assumes no prior science knowledge. The text supports main concepts with clinical applications, making them more relevant to students pursuing careers in the allied health field. The learning aids throughout the text, along with the reader-friendly writing style, create a highly-effective learning system for understanding the concepts of anatomy and physiology.

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Dissecting the Molecular Anatomy of Tissue (Principles and Practice)

Product Details
»Book Publisher: Springer (12 January, 2005)
»ISBN: 3540220062
»Book author: Michael R. Emmert-Buck, John W. Gillespie, Rodrigo F. Chuaqui
»Amazon Rating:

In Situ Hybridization Protocols (Methods in Molecular Biology)

In Situ Hybridization Protocols (Methods in Molecular Biology)



Product Details
»Book Publisher: Humana Press (September, 1994)
»ISBN: 0896032809
»Book author: K. H. Andy Choo



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Molecular Embryology: Methods and Protocols (Methods in Molecular Biology)

Molecular Embryology: Methods and Protocols (Methods in Molecular Biology)



Product Details
»Book Publisher: Humana Press (15 January, 1999)
»ISBN: 0896033872
»Book author: Paul T. Sharpe, Ivor Mason



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Cytokine Reference: A Compendium of Cytokines and Other Mediators of Host Defense (Institutional Version)

Cytokine Reference: A Compendium of Cytokines and Other Mediators of Host Defense (Institutional Version)

Product Details
»Book Publisher: Academic Press (September, 2000)
»ISBN: 0122526732
»Book author: Joost J. Oppenheim, Marc Feldman


Book Description:
The Cytokine Reference is the most complete work for anyone interested in the role of cytokines in host defense processes. With essential and comprehensive information on all known cytokines, including chemokines, growth factors and neuropeptides, the database will include hundreds of entries with detailed descriptions of cytokine genes, proteins, cell sources, activities, receptors, receptor signal transduction, gene activation, pathophysiology, therapeutics and techniques. This encyclopedic reference is written by a panel of global experts and will include extensive tables and diagrams. This book/online bundle consists of a two-volume print set, plus a regularly updated and searchable Online Database.
Cytokines are produced by virtually all the cells in our bodies, and they regulate the systems that defend us against infection, tumors, and trauma. This publication and database will enable all those working in the field to find the information they need about this ever-expanding field.

Key Features
* Online extensively-linked database is highly functional and allows you to reach data in a variety of ways–by cytokine, by cell type, or by disease
* Online version offers regularly updated entries and addition of new entries as research uncovers further information
* Print version has approximately 2500 pages of detailed and highly structured information on all the cytokines and other mediators of host defense
* Contains over 175 chapters contributed by international experts and edited by 6 world renowned scientists
* Online database allows extensive links at chapter subheading level guiding you through the maze of inter-relationships
* Online version includes full color diagrams and sequences plus links to online databases, including MEDLINE, PDB, SWISSPRO, and GenBank
* Every cytokine or receptor chapter uses the same highly structured subheadings, ensuring that the information is complete, comprehensive, and easy to find

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Methods in Enzymology, Volume 302: Green Flourescent Protein (Methods in Enzymology)

Methods in Enzymology, Volume 302: Green Flourescent Protein (Methods in Enzymology)

Product Details
»Book Publisher: Academic Press (15 April, 1999)
»ISBN: 0121822036
»Book author: John N. Abelson, Melvin I. Simon, P. Michael Conn
»Amazon Rating: 5.0

Book Description:
One of the most important recent discoveries in science is the green fluorescent protein, isolated from a bioluminescent jellyfish. The gene that codes for this protein is active in any type of cell, from microbes to humans, producing a “day-glo” dye visible as a bright green light in the microscope. The power of the gene is that by using recombinant DNA technology. GFP can be spliced to any protein, essentially painting that protein green. When such a spliced protein is inside a cell. Further, time-lapse microscopy can be used to examine how that protein and the cellular components that it is part of move within the cell during the cell’s life cycle.
This Methods in Enzymology volume deals with the utility of green fluorescent protein (GFP). The OVID database (including MEDLINE, Current Contents, and other sources) lists nine references to GFP for the ten-year period 1985-1994. In contrast, in less than four years thereafter, over 500 references are listed, a testament to the rapid growth of interest in this probe.
This volume documents many diverse uses for this interesting molecule in disciplines that broadly span biology. The methods presented include shortcuts and conveniences not included in previously published sources. The techniques are described in a context that allows comparisons to other related methodologies-such comparisons are valuable to readers who must adapt existing procedures to new systems. Also, so far as possible, methodologies have been presented in a manner that stresses their general applicability and potential limitations. The volume provides a substantial and current overview of the extant methodology in the field and a view of its rapid development.
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today–truly an essential publication for researchers in all fields of life sciences.

Key Features
* Monitoring of Physiological Processes
* Localization of Molecules
* Special Uses
* Mutants
* Variants of GFP

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Kinesin Protocols (Methods in Molecular Biology)

Kinesin Protocols (Methods in Molecular Biology)



Product Details
»Book Publisher: Humana Press (15 January, 2001)
»ISBN: 0896037665
»Book author: Isabelle Vernos



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Molecular Biology Problem Solver: A Laboratory Guide

Molecular Biology Problem Solver: A Laboratory Guide

Product Details
»Book Publisher: Wiley-Liss (24 August, 2001)
»ISBN: 0471379727
»Book author: Alan S. Gerstein
»Amazon Rating:

Book Description:
Most research in the life sciences involves a core set of molecular-based equipment and methods, for which there is no shortage of step-by-step protocols. Nonetheless, there remains an exceedingly high number of inquiries placed to commercial technical support groups, especially regarding problems.

Molecular Biology Problem Solver: A Laboratory Guide asks the reader to consider crucial questions, such as:

• Have you selected the most appropriate research strategy?
• Have you identified the issues critical to your successful application of a technique?
• Are you familiar with the limitations of a given technique?
• When should common procedural rules of thumb not be applied?
• What strategies could you apply to resolve a problem?

A unique question-based format reviews common assumptions and laboratory practices, with the aim of offering a firm understanding of how techniques and procedures work, as well as how to avoid problems. Some major issues explored by the book’s expert contributors include:

• Working safely with biological samples and radioactive materials
• DNA and RNA purification
• PCR
• Protein and nucleid acid hybridization
• Prokaryotic and eukaryotic expression systems
• Properly using and maintaining laboratory equipment

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Cell Motility: From Molecules to Organisms (Life Sciences)

Cell Motility: From Molecules to Organisms (Life Sciences)




Product Details
»Book Publisher: John Wiley & Sons (17 March, 2004)
»ISBN: 0470848723
»Book author: Anne Ridley, Michelle Peckham, Peter Clark
»Amazon Rating:

Book Description:
Recent advances in molecular and biophysical techniques, particularly fluorescence and live cell imaging, are revolutionizing the study of cell motility. New bioprobes not only reveal simple intracellular localization, but also contain details of post-translational modifications, conformational state and protein-protein interactions. Coupling these insights with complementary advances in genetic and biochemical methods is enabling scientists to understand the processes involved in cell motility - from molecular motors to cell movements in vivo in a range of organisms and cell types.

This book features landmark essays that provide an up to date and fascinating account of current research and concepts in cell motility.These cover the roles of molecular motors that drive movement and their interactions with the cytoskeleton as well as membrane dynamics that allow cells to change shape and to move.

Cell motility plays a key role in development - there are chapters on the genetics of cell migration, the regulation of contact repulsion in growth cones, and the progression from cell migration to cell-cell adhesion. Cell motility is directional - experts describe the molecules that regulate chemotaxis, allowing cells to migrate along pathways specified by chemical gradients. Finally, cell motility can be perturbed by mutation–metastasis occurs when cells lose their normal intercellular interactions and invade other tissue types. All these processes are regulated by signals from the environment, including other tissues in the body, and the various molecules that transmit and transduce these signals are discussed.

This book is a ‘must read’ for cell biologists working in a variety of fields, from development to wound healing, at all levels - post-doctoral fellows, post-graduate students and lab technicians. It is also stimulating reading for molecular and developmental biologists, biophysicists and biochemists.


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Adipose Tissue Protocals (Methods in Molecular Biology)

Adipose Tissue Protocals (Methods in Molecular Biology)

Product Details
»Book Publisher: Humana Press (15 February, 2001)
»ISBN: 0896037479
»Book author: Gerard Aihaud, Gerard Ailhaud


Book Description:
Universite de Nice-Sophia Antipolis, France. Describes key techniques for the study of adipose tissue and cells, discusses common errors and potential problems of each method, covers transfection of adipocytes and quantification of lipid-related mRNAs, and includes step-by-step instructions. DNLM: Adipose Tissue–cytology.

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Molecular Evolution: Producing the Biochemical Data, Volume 224: Volume 224: Molecular Evolution (Methods in Enzymology)

Molecular Evolution: Producing the Biochemical Data, Volume 224: Volume 224: Molecular Evolution (Methods in Enzymology)



Product Details
»Book Publisher: Academic Press (12 October, 1993)
»ISBN: 0121821250
»Book author: John N. Abelson, Melvin I. Simon, Elizabeth A. Zimmer, Thomas J. White, Rebecca L. Cann, Allan C. Wilson


Book Description:
This book provides a single source of information for all molecular methods. Expert advice is given on sample collection and storage for molecular work.



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Oncogene Techniques (Methods in Enzymology)

Oncogene Techniques (Methods in Enzymology)



Product Details
»Book Publisher: Academic Press (27 July, 2006)
»ISBN: 0121821552
»Book author: Colowick, Melvin I. Simon, Gregory Peter Ed. Peter Ed. Vogt
»Amazon Rating: 4.0

Book Description:
General Description of the Volume:
Oncogenes have become a central focus of cancer research. All involved in this discipline will find this volume an invaluable aid in developing protocols needed for their research.
General Description of the Series:
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today–truly an essential publication for researchers in all fields of life sciences.

Key Features
* Cell culture
* Molecular cloning
* Gene function
* Protein-protein interactions
* Protein-DNA interactions



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Methods in Enzymology, Volume 356: Laser Capture in Microscopy and Microdissection (Methods in Enzymology)

Methods in Enzymology, Volume 356: Laser Capture in Microscopy and Microdissection (Methods in Enzymology)

Product Details
»Book Publisher: Academic Press (October, 2002)
»ISBN: 0121822591
»Book author: P. Michael Conn


Book Description:
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences.

Major Sections Include:
* Basic Principles, Specialized Uses, and Genetic Applications
* LCM and its application in genomics and proteomics * Fluorescence in situ hybridization of LCM isolated nuclei from paraffin sections
* Noncontact laser catapulting for the functional genomics and proteomics
* Use of LCM for clonal analysis, in carcinoma analysis, to assess development, in complex tissue, in pathology, gene discovery, and more.

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Nuclear Receptors, Volume 364 (Methods in Enzymology)

Nuclear Receptors, Volume 364 (Methods in Enzymology)

Product Details
»Book Publisher: Academic Press (10 November, 2003)
»ISBN: 0121822672
»Book author: David W. Russell
»Amazon Rating: 4.0

Book Description:
Nuclear Receptors are inducible transcription factors that mediate complex effects on development, differentiation and homeostasis. They regulate the transcription of their target genes through binding to DNA sequences.

*Analysis of Nuclear Receptor Ligands
*Structure/Function Analysis of Nuclear Receptors
*Analysis of Nuclear Receptor Co-Factors and Chromatin Remodeling

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Proteolytic Enzymes: Aspartic and Metallo Peptidases (Methods in Enzymology)

Proteolytic Enzymes: Aspartic and Metallo Peptidases (Methods in Enzymology)

Product Details
»Book Publisher: Academic Press (15 July, 1995)
»ISBN: 0121821498
»Book author: John N. Abelson, Melvin I. Simon, Alan J. Barrett
»Amazon Rating:

Book Description:
In this volume of Methods in Enzymology and its companion Volume 244, the chapters on specific methods, enzymes, and inhibitors are organized within the rational framework of the new systems for classificationand nomenclature. A wide variety of specificities of peptide bond hydrolysis are represented in each set of peptidases, together with an equally wide range of biological functions.

Key Features
* Aspartic peptidases
* Metallopeptidases
* New information on classification of proteolytic enzymes
* Medical implications of research in this area
* Biotechnological uses of these enzymes

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RNA Polymerase and Associated Factors: Part B (Methods in Enzymology)

RNA Polymerase and Associated Factors: Part B (Methods in Enzymology)



Product Details
»Book Publisher: Academic Press (15 October, 1996)
»ISBN: 0121821757
»Book author: John N. Abelson, Melvin I. Simon, Sankar Adhya
»Amazon Rating:

Book Description:
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 270 volumes have been published (all of them still in print) and much of the material is relevant even today–truly an essential publication for researchers in all fields of life sciences.

Key Features
* Basal transcription and regulation of transcription: transcription factors, activators, and repressors
* Chromatin as templates for transcription
* Transcription elongation and termination: factors and complexes
* Specialized techniques



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Signal Transduction

Signal Transduction

Product Details
»Book Publisher: Academic Press (March, 2002)
»ISBN: 0122896319
»Book author: Bastien D. Gomperts, Ijsbrand M. Kramer, Peter E.R. Tatham
»Amazon Rating: 4.0

Book Description:
Signal Transduction is a well-illustrated, coherent look at cellular signaling processes. Beginning with the basics, it explains how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and then shows how these inputs are integrated and coordinated. The extensive color artwork provides the reader with a clearer comprehension of key topics, and margin notes are incorporated to highlight milestones in the evolution of signal transduction. This book serves as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields.

Key Features
* Coherent, precise text providing insight in depth to a subject that is central to cell biology and fundamental to many areas of biomedicine
* Extensive conceptual colour artwork assists with the comprehension of key topics
* Extensive referencing provides an invaluable link to the core and historical literature
* Margin notes highlighting milestones in the evolution of our understanding of signalling mechanisms

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Rna-Protein Interaction Protocols (Methods in Molecular Biology)

Rna-Protein Interaction Protocols (Methods in Molecular Biology)




Product Details
»Book Publisher: Humana Press (15 August, 1999)
»ISBN: 0896035689
»Book author: Susan R. Haynes
»Amazon Rating: 3.0

Book Description:
Uniformed Services Univ. of the Health Sciences, Bethesda, MD. Presents techniques for analyzing how proteins and RNA interact. For researchers. Expanded-outline format.


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