Clinical Mycology
BY
Elias J. Anaissie (Editor), Michael R. McGinnis (Editor), Michael Pfaller (Editor)
Product Details
SIZE = 3.8 MB
FORMAT = PDF
Hardcover: 768 pages
Publisher: Churchill Livingstone; 1 edition (July 15, 2002)
Language: English
ISBN-10: 0443079374
ISBN-13: 978-0443079375
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Editorial Reviews
From the New England Journal of Medicine, August 14, 2003
The diagnosis and treatment of invasive fungal infections are no longer relegated to a few
experts at academic medical centers. On the contrary, the increasing incidence of such infections
has made it crucial that a broad spectrum of clinicians become knowledgeable about them.
Moreover, the emergence of infections caused by fungi other than candida or aspergillus species
underscores the need for clinicians to be well versed in the signs and symptoms, the appropriate
diagnostic tests, and the treatment of a range of these infections. The editors of Clinical
Mycology, who have themselves made substantial contributions to the renaissance in clinical
mycology, enlisted an impressive group of investigators in order to create this textbook. The
exceptional strength of the book is that all the authors are known not only for their basic
research, but also for their clinical expertise. This dual expertise is evident in the clarity
with which each chapter is written. The opening chapters set the stage for this exceptional book.
After an impressive array of color plates, the epidemiology of invasive fungal disease is clearly
outlined by Pfaller and Wenzel. The data presented in the brilliant chapters on the pathogenesis
of fungal infections (by Cole) and on the immunology of these infections (by Harrison and Levitz)
should form the cornerstone for the determination of risks and the treatment of invasive fungal
disease now and in the future. Every chapter provides not only clinical pearls, but also the
rationale for these pearls. The chapter on antifungal therapy (by Revankar and Graybill) provides
a historical perspective. It contains excellent discussions of testing for susceptibility to
antifungal agents and an appropriate perspective on combination therapy -- a treatment strategy
that is still in its infancy, with little more than anecdotal data to support it. Two new agents,
voriconazole and caspofungin, which were licensed within months of the publication of this book,
and other drugs now in the pipeline are discussed in this chapter, but they receive only limited
notice in the chapters on the treatment of specific diseases. The chapters on individual
pathogens and diseases are comprehensive. The discussion of fungal infections that can develop
subsequent to hematopoietic-cell transplantation, however, is limited. This problem accounts for
a considerable proportion of invasive mold infections. Patients who become infected with fungi
after hematopoietic stem-cell transplantation have a high mortality despite treatment, and the
coexisting conditions that are common in these patients affect the tolerability of antifungal
agents. Nevertheless, this deficiency does not diminish the overall usefulness of this book.
Clinical Mycology is definitely a "must read" or, at least, a "should have on hand" for all
clinicians, pathologists, and microbiologists involved in the care of any of the growing number
of patients who are susceptible to invasive fungal disease. Janice Brown, M.D.
Copyright © 2003 Massachusetts Medical Society. All rights reserved. The New England Journal of
Medicine is a registered trademark of the MMS.
Book Description
The first textbook of mycology ever to focus on the management of patients with fungal
infections, CLINICAL MYCOLOGY represents an expert, authoritative examination of clinical
problem-solving approaches to diagnosis and management. It offers specific recommendations for
understanding, controlling, and preventing fungal infections based on underlying principles of
epidemiology and infection control policy, pathogenesis, immunology, histopathology, and
laboratory diagnosis and antifungal therapy. The book also covers etiologic agents of disease,
fungal infections in special hosts such as pediatric patients and patients with cancer or HIV,
infections of the organ systems, and more. Extensive illustrations, tables, and photographs
throughout the book highlight its clinical context and enhance the reader's understanding of the
subject.
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