Mycology

Clinical Mycology




BY
Elias J. Anaissie (Editor), Michael R. McGinnis (Editor), Michael Pfaller (Editor)



Product Details

SIZE = 3.8 MB
FORMAT = PDF
Hardcover: 768 pages
Publisher: Churchill Livingstone; 1 edition (July 15, 2002)
Language: English
ISBN-10: 0443079374
ISBN-13: 978-0443079375



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Editorial Reviews

From the New England Journal of Medicine, August 14, 2003
The diagnosis and treatment of invasive fungal infections are no longer relegated to a few

experts at academic medical centers. On the contrary, the increasing incidence of such infections

has made it crucial that a broad spectrum of clinicians become knowledgeable about them.

Moreover, the emergence of infections caused by fungi other than candida or aspergillus species

underscores the need for clinicians to be well versed in the signs and symptoms, the appropriate

diagnostic tests, and the treatment of a range of these infections. The editors of Clinical

Mycology, who have themselves made substantial contributions to the renaissance in clinical

mycology, enlisted an impressive group of investigators in order to create this textbook. The

exceptional strength of the book is that all the authors are known not only for their basic

research, but also for their clinical expertise. This dual expertise is evident in the clarity

with which each chapter is written. The opening chapters set the stage for this exceptional book.

After an impressive array of color plates, the epidemiology of invasive fungal disease is clearly

outlined by Pfaller and Wenzel. The data presented in the brilliant chapters on the pathogenesis

of fungal infections (by Cole) and on the immunology of these infections (by Harrison and Levitz)

should form the cornerstone for the determination of risks and the treatment of invasive fungal

disease now and in the future. Every chapter provides not only clinical pearls, but also the

rationale for these pearls. The chapter on antifungal therapy (by Revankar and Graybill) provides

a historical perspective. It contains excellent discussions of testing for susceptibility to

antifungal agents and an appropriate perspective on combination therapy -- a treatment strategy

that is still in its infancy, with little more than anecdotal data to support it. Two new agents,

voriconazole and caspofungin, which were licensed within months of the publication of this book,

and other drugs now in the pipeline are discussed in this chapter, but they receive only limited

notice in the chapters on the treatment of specific diseases. The chapters on individual

pathogens and diseases are comprehensive. The discussion of fungal infections that can develop

subsequent to hematopoietic-cell transplantation, however, is limited. This problem accounts for

a considerable proportion of invasive mold infections. Patients who become infected with fungi

after hematopoietic stem-cell transplantation have a high mortality despite treatment, and the

coexisting conditions that are common in these patients affect the tolerability of antifungal

agents. Nevertheless, this deficiency does not diminish the overall usefulness of this book.

Clinical Mycology is definitely a "must read" or, at least, a "should have on hand" for all

clinicians, pathologists, and microbiologists involved in the care of any of the growing number

of patients who are susceptible to invasive fungal disease. Janice Brown, M.D.
Copyright © 2003 Massachusetts Medical Society. All rights reserved. The New England Journal of

Medicine is a registered trademark of the MMS.

Book Description
The first textbook of mycology ever to focus on the management of patients with fungal

infections, CLINICAL MYCOLOGY represents an expert, authoritative examination of clinical

problem-solving approaches to diagnosis and management. It offers specific recommendations for

understanding, controlling, and preventing fungal infections based on underlying principles of

epidemiology and infection control policy, pathogenesis, immunology, histopathology, and

laboratory diagnosis and antifungal therapy. The book also covers etiologic agents of disease,

fungal infections in special hosts such as pediatric patients and patients with cancer or HIV,

infections of the organ systems, and more. Extensive illustrations, tables, and photographs

throughout the book highlight its clinical context and enhance the reader's understanding of the

subject.


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