Calpain Methods and Protocols (Methods in Molecular Biology)
Product Details
»Book Publisher: Humana Press (March, 2000)
»ISBN: 0896036324
»Book author: John S. Elce
Book Description:
Queen’s Univ. Kingston, Ontario, Canada. Set of proven and easily followed protocols for studying calpain. Detailed methods to investigate the physiological and pathological roles of calpain. A wide range of calpain systems and tissue models. Specific lists Specific lists of all required materials and notes on pitfalls.
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Showing posts with label Biochemistry. Show all posts
Showing posts with label Biochemistry. Show all posts
Inflammation Protocols (Methods in Molecular Biology, V. 225)
Product Details
»Book Publisher: Humana Press (April, 2003)
»ISBN: 0896039706
»Book author: Paul G. Winyard, D. A. Willoughby
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Calcium-Binding Protein Protocols: Volume 1: Reviews and Case Histories (Methods in Molecular Biology)
Calcium-Binding Protein Protocols: Volume 1: Reviews and Case Histories (Methods in Molecular Biology)
Product Details
»Book Publisher: Humana Press (15 December, 2001)
»ISBN: 089603688X
»Book author: Hans J. Vogel
Book Description:
Blurb for Volume 1 Hans Vogel and a panel of leading researchers review the protein chemistry and behavior of this significant protein class, and provide a comprehensive collection of proven experimental techniques for their study both in vitro and in vivo. This first volume discusses the role of calcium in intracellular secondary messenger activation mechanisms, including unique aspects of calcium chemistry and its utilization in diary proteins and blood clotting. Detailed case studies provide a wealth of valuable information about protein purification and characterization strategies, X-ray crystallography, and specific calcium-binding proteins and their modes of action. The second companion volume focuses on cutting-edge experimental methods for studying solution structure, stability, dynamics, calcium-binding properties, and biological activity of calcium-binding proteins in general. Single Blurb for Both Volumes: Hans Vogel and a panel of leading researchers review the protein chemistry and behavior of this significant protein class, and provide a comprehensive collection of proven experimental techniques for their study both in vitro and in vivo. The first volume discusses the role of calcium in intracellular secondary messenger activation mechanisms, including unique aspects of calcium chemistry and its utilization in dairy proteins and blood clotting. Detailed case studies provide a wealth of valuable information about protein purification and characterization strategies, X-ray crystallography, and specific calcium-binding proteins and their modes of action. The second volume focuses on cutting–edge experimental techniques for studying the solution structure, stability, dynamics, calcium-binding properties, and biological activity of calcium-binding protein in general. In addition to enzymatic assays and more routine spectroscopic and protein chemistry techniques, there are also NMR approaches, thermodynamic analyses, kinetic measurements such as surface plasmon resonance, strategies for amino acid sequence alignments, and fluorescence methods to study the distribution of calcium and calcium–binding proteins in cells.
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Cytokine Reference: A Compendium of Cytokines and Other Mediators of Host Defense (Institutional Version)
Cytokine Reference: A Compendium of Cytokines and Other Mediators of Host Defense (Institutional Version)
Product Details
»Book Publisher: Academic Press (September, 2000)
»ISBN: 0122526732
»Book author: Joost J. Oppenheim, Marc Feldman
Book Description:
The Cytokine Reference is the most complete work for anyone interested in the role of cytokines in host defense processes. With essential and comprehensive information on all known cytokines, including chemokines, growth factors and neuropeptides, the database will include hundreds of entries with detailed descriptions of cytokine genes, proteins, cell sources, activities, receptors, receptor signal transduction, gene activation, pathophysiology, therapeutics and techniques. This encyclopedic reference is written by a panel of global experts and will include extensive tables and diagrams. This book/online bundle consists of a two-volume print set, plus a regularly updated and searchable Online Database.
Cytokines are produced by virtually all the cells in our bodies, and they regulate the systems that defend us against infection, tumors, and trauma. This publication and database will enable all those working in the field to find the information they need about this ever-expanding field.
Key Features
* Online extensively-linked database is highly functional and allows you to reach data in a variety of ways–by cytokine, by cell type, or by disease
* Online version offers regularly updated entries and addition of new entries as research uncovers further information
* Print version has approximately 2500 pages of detailed and highly structured information on all the cytokines and other mediators of host defense
* Contains over 175 chapters contributed by international experts and edited by 6 world renowned scientists
* Online database allows extensive links at chapter subheading level guiding you through the maze of inter-relationships
* Online version includes full color diagrams and sequences plus links to online databases, including MEDLINE, PDB, SWISSPRO, and GenBank
* Every cytokine or receptor chapter uses the same highly structured subheadings, ensuring that the information is complete, comprehensive, and easy to find
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Kinesin Protocols (Methods in Molecular Biology)
Product Details
»Book Publisher: Humana Press (15 January, 2001)
»ISBN: 0896037665
»Book author: Isabelle Vernos
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Protein Purification Protocols (Methods in Molecular Biology)
Product Details
»Book Publisher: Humana Press (15 June, 1996)
»ISBN: 0896033368
»Book author: Shawn Doonan
»Amazon Rating: 5.0
Book Description:
University of East London, U.K. Manual on laboratory methods on protein isolation for students or researchers new to the technique. Includes a chapter on chromatography. Plastic comb spiral binding. 33 contributors, 3 U.S.
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Cell Motility: From Molecules to Organisms (Life Sciences)
Product Details
»Book Publisher: John Wiley & Sons (17 March, 2004)
»ISBN: 0470848723
»Book author: Anne Ridley, Michelle Peckham, Peter Clark
»Amazon Rating:
Book Description:
Recent advances in molecular and biophysical techniques, particularly fluorescence and live cell imaging, are revolutionizing the study of cell motility. New bioprobes not only reveal simple intracellular localization, but also contain details of post-translational modifications, conformational state and protein-protein interactions. Coupling these insights with complementary advances in genetic and biochemical methods is enabling scientists to understand the processes involved in cell motility - from molecular motors to cell movements in vivo in a range of organisms and cell types.
This book features landmark essays that provide an up to date and fascinating account of current research and concepts in cell motility.These cover the roles of molecular motors that drive movement and their interactions with the cytoskeleton as well as membrane dynamics that allow cells to change shape and to move.
Cell motility plays a key role in development - there are chapters on the genetics of cell migration, the regulation of contact repulsion in growth cones, and the progression from cell migration to cell-cell adhesion. Cell motility is directional - experts describe the molecules that regulate chemotaxis, allowing cells to migrate along pathways specified by chemical gradients. Finally, cell motility can be perturbed by mutation–metastasis occurs when cells lose their normal intercellular interactions and invade other tissue types. All these processes are regulated by signals from the environment, including other tissues in the body, and the various molecules that transmit and transduce these signals are discussed.
This book is a ‘must read’ for cell biologists working in a variety of fields, from development to wound healing, at all levels - post-doctoral fellows, post-graduate students and lab technicians. It is also stimulating reading for molecular and developmental biologists, biophysicists and biochemists.
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Transmembrane Transporters (Receptor Biochemistry and Methodology)
Product Details
»Book Publisher: Wiley-Liss (09 September, 2002)
»ISBN: 0471065137
»Book author: Michael W. Quick
»Amazon Rating:
Book Description:
A must-have far-reaching text that provides readers with a state-of-the-art molecule update on transmembrane transporters, focusing on the methodological approaches currently employed to better understand how transporters work and how they can be used in cutting edge therapies. Each chapter begins with an overview of the importnat biological questions presently being considered in their field, then presents scientific approaches to address these questions. In explaining approaches, the authors cover bench-top protocols, conceptual frameworks, data obtained, and pitfalls common to the techniques.
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Glycoprotein Methods & Protocols The Mucins (Methods in Molecular Biology)
Product Details
»Book Publisher: Humana Press (15 March, 2000)
»ISBN: 0896037207
»Book author: Anthony P. Corfield
Book Description:
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Oxidants and Antioxidants: Ultrastructural and Molecular Biology Protocols (Methods in Molecular Biology)
Oxidants and Antioxidants: Ultrastructural and Molecular Biology Protocols (Methods in Molecular Biology)
Product Details
»Book Publisher: Humana Press (15 July, 2002)
»ISBN: 0896038513
»Book author: Donald Armstrong
Book Description:
Univ. of Florida, Gainesville. Provides a comprehensive collection of ultrastructure and molecular tools for the evaluation of metabolic disorders linked to oxidative stress and the aging process. Features a readily reproducible format, techniques for using X-ray, electron, and spectral spatial paramagnetic resonance. Expanded-outline format.
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Nuclear Receptors, Volume 364 (Methods in Enzymology)
Product Details
»Book Publisher: Academic Press (10 November, 2003)
»ISBN: 0121822672
»Book author: David W. Russell
»Amazon Rating: 4.0
Book Description:
Nuclear Receptors are inducible transcription factors that mediate complex effects on development, differentiation and homeostasis. They regulate the transcription of their target genes through binding to DNA sequences.
*Analysis of Nuclear Receptor Ligands
*Structure/Function Analysis of Nuclear Receptors
*Analysis of Nuclear Receptor Co-Factors and Chromatin Remodeling
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Protein NMR Techniques (Methods in Molecular Biology)
Product Details
»Book Publisher: Humana Press (15 August, 1997)
»ISBN: 0896033090
»Book author: David G. Reid
Book Description:
SmithKline Beecham Pharmaceuticals, Hertfordshire, U.K. Text on how to apply the fundamentals of NMR to the study of proteins. For chemists and biochemists. 29 contributors, 26 U.S.
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Protein Targeting Protocols (Methods in Molecular Biology)
Product Details
»Book Publisher: Humana Press (June, 1998)
»ISBN: 089603450X
»Book author: Roger A. Clegg
»Amazon Rating:
Book Description:
Hannah Research Institute, Scotland, UK. Text of methods for detecting and analyzing the proteins and protein motifs involved in cellular targeting interactions. Modified-outline format. Plasticcomb binding, hardcover available.
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Proteolytic Enzymes: Aspartic and Metallo Peptidases (Methods in Enzymology)
Product Details
»Book Publisher: Academic Press (15 July, 1995)
»ISBN: 0121821498
»Book author: John N. Abelson, Melvin I. Simon, Alan J. Barrett
»Amazon Rating:
Book Description:
In this volume of Methods in Enzymology and its companion Volume 244, the chapters on specific methods, enzymes, and inhibitors are organized within the rational framework of the new systems for classificationand nomenclature. A wide variety of specificities of peptide bond hydrolysis are represented in each set of peptidases, together with an equally wide range of biological functions.
Key Features
* Aspartic peptidases
* Metallopeptidases
* New information on classification of proteolytic enzymes
* Medical implications of research in this area
* Biotechnological uses of these enzymes
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Small Gtpases & Their Regulators: Part A: Ras Family (Methods in Enzymology)
Product Details
»Book Publisher: Academic Press (27 July, 2006)
»ISBN: 0121821560
»Book author: Colowick, W. E. Balch, W.E. Ed. Balch
»Amazon Rating:
Book Description:
General Description of the Volume:
Small GTPases play a key role in many aspects of contemporary cell biology: control of cell growth and differentiation; regulation of cell adhesion and cell movement; the organization of the actin cytoskeleton; and the regulation of intracellular vesicular transport. This volume plus its companions Volumes 256 and 257 cover all the biochemical and biological assays currently in use for analyzing the role of small GTPases in many aspects of cell biology at the molecular level.
General Description of the Series:
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today–truly an essential publication for researchers in all fields of life sciences.
Key Features
* Expression, purification, and posttranslational modification
* Guanine nucleotide exchange and hydrolysis
* Cell expression and analysis in Vitro
* Biological activity
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RNA Polymerase and Associated Factors: Part B (Methods in Enzymology)
Product Details
»Book Publisher: Academic Press (15 October, 1996)
»ISBN: 0121821757
»Book author: John N. Abelson, Melvin I. Simon, Sankar Adhya
»Amazon Rating:
Book Description:
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 270 volumes have been published (all of them still in print) and much of the material is relevant even today–truly an essential publication for researchers in all fields of life sciences.
Key Features
* Basal transcription and regulation of transcription: transcription factors, activators, and repressors
* Chromatin as templates for transcription
* Transcription elongation and termination: factors and complexes
* Specialized techniques
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RNA Polymerase and Associated Factors, Part D, Volume 371 (Methods in Enzymology)
Product Details
»Book Publisher: Academic Press (16 December, 2003)
»ISBN: 0121822745
»Book author: Sankar Adhya, Susan Garges
Book Description:
RNA polymerase is molecule important to gene transcription. Along with associated factors, RNA polymerase is part of the process in which RNA is transcribed to produce a protein.
* Models and methods for studying polymerase translocation
* Assay for movements of RNA polymerase along DNA
* Engineering of elongation complexes of bacterial and yeast RNA polymerases
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Signal Transduction
Product Details
»Book Publisher: Academic Press (March, 2002)
»ISBN: 0122896319
»Book author: Bastien D. Gomperts, Ijsbrand M. Kramer, Peter E.R. Tatham
»Amazon Rating: 4.0
Book Description:
Signal Transduction is a well-illustrated, coherent look at cellular signaling processes. Beginning with the basics, it explains how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and then shows how these inputs are integrated and coordinated. The extensive color artwork provides the reader with a clearer comprehension of key topics, and margin notes are incorporated to highlight milestones in the evolution of signal transduction. This book serves as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields.
Key Features
* Coherent, precise text providing insight in depth to a subject that is central to cell biology and fundamental to many areas of biomedicine
* Extensive conceptual colour artwork assists with the comprehension of key topics
* Extensive referencing provides an invaluable link to the core and historical literature
* Margin notes highlighting milestones in the evolution of our understanding of signalling mechanisms
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RNA Polymerase and Associated Factors, Part C, Volume 370 (Methods in Enzymology)
Product Details
»Book Publisher: Academic Press (16 December, 2003)
»ISBN: 0121822737
»Book author: Sankar Adhya, Susan Garges
»Amazon Rating:
Book Description:
RNA polymerase is molecule important to gene transcription. Along with associated factors, RNA polymerase is part of the process in which RNA is transcribed to produce a protein.
* Construction and purification of RNA polymerases
* DNA microarrays and bacterial gene expression
* Functional analysis of transcription factors
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Interleukin Protocols (Methods in Molecular Medicine)
Product Details
»Book Publisher: Humana Press (July, 2001)
»ISBN: 089603738X
»Book author: Luke A. J. O’Neill, Andrew Bowie
Book Description:
Trinity College, Dublin, Ireland. Text offering biomedical researchers a collection of the major techniques used to assess the role of interleukins in disease, to facilitate diagnosis, and to speed the creation of new therapies. Features halftone illustrations. Designed as a laboratory manual for researchers.
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